San Francisco 49ers Head-to-Head Records
Last updated: April 15, 2026
2025 season · 10 tracked opponents
The San Francisco 49ers have tracked head-to-head records against 10 opponents in 2025. Browse each matchup below for ATS, total, and last-meeting breakdowns.
TRACKED OPPONENTS
10
TOTAL MEETINGS
90
Head-to-Head Opponents
| Opponent | Record | Games | Last Meeting |
|---|---|---|---|
| vs Seattle Seahawks | 9-9 | 18 | 2026-01-17 |
| vs Los Angeles Rams | 10-7 | 17 | 2025-11-09 |
| vs Arizona Cardinals | 9-7 | 16 | 2025-11-16 |
| vs Green Bay Packers | 4-4 | 8 | 2024-11-24 |
| vs Tampa Bay Buccaneers | 4-2 | 6 | 2025-10-12 |
| vs Dallas Cowboys | 4-1 | 5 | 2024-10-27 |
| vs Philadelphia Eagles | 3-2 | 5 | 2026-01-11 |
| vs Chicago Bears | 3-2 | 5 | 2025-12-28 |
| vs Minnesota Vikings | 2-3 | 5 | 2024-09-15 |
| vs Kansas City Chiefs | 0-5 | 5 | 2024-10-20 |
Ask Optimus about San Francisco 49ers head-to-head records
Pick a starter or type your own. First query is free.
More San Francisco 49ers Trend Records
Frequently Asked Questions
How many opponents have the San Francisco 49ers played this season?▾
The San Francisco 49ers have tracked head-to-head records against 10 opponents this season.
Which opponents have the San Francisco 49ers played most often?▾
See the opponents table above for a full matchup-by-matchup record breakdown.
How far back does the San Francisco 49ers H2H data go?▾
Current-season H2H pages cover this season. Last-5-years H2H pages go back through the previous five full seasons.
Where can I see other San Francisco 49ers betting records?▾
Beyond head-to-head, we track San Francisco 49ers ATS, moneyline, over/under, home/away, and situational records — see the links below.
What's the difference between the current and 5-year pages?▾
Current-season H2H covers this season's meetings. Last-5-years H2H records all meetings from the past five full seasons — useful for longer-term matchup trends.