Trendline Labs
MLBHead-to-HeadAll-Time

San Francisco Giants vs St. Louis Cardinals · All-Time

Last updated: April 15, 2026

46 meetings tracked · closing-line graded

Across 46 all-time head-to-head meetings, St. Louis Cardinals lead 27-19. Games have averaged 9.3 combined points.

RECORD

19-27

MEETINGS

46

ATS

11-15

O / U

15-11

Key Insights

  • St. Louis Cardinals lead 27-19 across 46 tracked meetings.
  • Games have averaged 9.3 combined points.
  • St. Louis Cardinals have been the better ATS side (15-11).
  • Strong Over trend: 15-11 O/U.

Year-by-Year Record

SeasonGamesSan Francisco GiantsSt. Louis CardinalsATSO / UAvg Total
20256243-33-39.5
20246151-55-19.8
20237615-23-49.0
20227342-54-310.7
20216247.0
20197348.3
201872510.3

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Frequently Asked Questions

What is the San Francisco Giants vs St. Louis Cardinals record all-time?

Across 46 all-time meetings, the St. Louis Cardinals lead the series 27-19.

What is the ATS trend in San Francisco Giants vs St. Louis Cardinals games?

ATS: San Francisco Giants are 11-15 vs the spread in these matchups. St. Louis Cardinals are 15-11.

Do San Francisco Giants vs St. Louis Cardinals games go over or under?

Over/under: games between San Francisco Giants and St. Louis Cardinals have gone over 15 times and under 11 times, with an average combined score of 9.3.

When did San Francisco Giants and St. Louis Cardinals last play?

See Last Meetings section for detailed score, spread, and total data from the most recent San Francisco Giants vs St. Louis Cardinals games.

Where can I see the 5-year San Francisco Giants vs St. Louis Cardinals history?

A 5-year head-to-head page tracks every San Francisco Giants vs St. Louis Cardinals meeting from the last five full seasons. Link at the bottom of this page.

Data coverage: Trendline's head-to-head records include closing-line-graded games from 20182025. Older meetings aren't in this dataset yet.

Head-to-head data derived from closing-line game records. Stats update nightly from graded game results.

For informational and entertainment purposes only. Not betting advice. Please gamble responsibly.

Optimus

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