Trendline Labs
MLBHead-to-HeadAll-Time

Chicago White Sox vs St. Louis Cardinals · All-Time

Last updated: April 15, 2026

19 meetings tracked · closing-line graded

Across 19 all-time head-to-head meetings, St. Louis Cardinals lead 12-7. Games have averaged 8.3 combined points.

RECORD

7-12

MEETINGS

19

ATS

3-6

O / U

4-4

Key Insights

  • St. Louis Cardinals lead 12-7 across 19 tracked meetings.
  • Games have averaged 8.3 combined points.
  • St. Louis Cardinals have been the better ATS side (6-3).

Year-by-Year Record

SeasonGamesChicago White SoxSt. Louis CardinalsATSO / UAvg Total
20253031-212.3
20243212-11-26.7
20233121-28.3
20213217.0
20203128.0
20184137.5

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Frequently Asked Questions

What is the Chicago White Sox vs St. Louis Cardinals record all-time?

Across 19 all-time meetings, the St. Louis Cardinals lead the series 12-7.

What is the ATS trend in Chicago White Sox vs St. Louis Cardinals games?

ATS: Chicago White Sox are 3-6 vs the spread in these matchups. St. Louis Cardinals are 6-3.

Do Chicago White Sox vs St. Louis Cardinals games go over or under?

Over/under: games between Chicago White Sox and St. Louis Cardinals have gone over 4 times and under 4 times, with an average combined score of 8.3.

When did Chicago White Sox and St. Louis Cardinals last play?

See Last Meetings section for detailed score, spread, and total data from the most recent Chicago White Sox vs St. Louis Cardinals games.

Where can I see the 5-year Chicago White Sox vs St. Louis Cardinals history?

A 5-year head-to-head page tracks every Chicago White Sox vs St. Louis Cardinals meeting from the last five full seasons. Link at the bottom of this page.

Data coverage: Trendline's head-to-head records include closing-line-graded games from 20182025. Older meetings aren't in this dataset yet.

Head-to-head data derived from closing-line game records. Stats update nightly from graded game results.

For informational and entertainment purposes only. Not betting advice. Please gamble responsibly.

Optimus

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