Trendline
MLBHead-to-HeadAll-Time

Chicago White Sox vs San Diego Padres · All-Time

Last updated: April 15, 2026

15 meetings tracked · closing-line graded

Across 15 all-time head-to-head meetings, San Diego Padres lead 10-5. Games have averaged 6.1 combined points.

RECORD

5-10

MEETINGS

15

ATS

10-5

O / U

2-11

Key Insights

  • San Diego Padres lead 10-5 across 15 tracked meetings.
  • Games have averaged 6.1 combined points.
  • Chicago White Sox have been the better ATS side (10-5).
  • Strong Under trend: 2-11 O/U.

Year-by-Year Record

SeasonGamesChicago White SoxSan Diego PadresATSO / UAvg Total
20263211-27.0
20253122-11-27.3
20243031-26.3
20233032-15.0
20223212-14.7

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Frequently Asked Questions

What is the Chicago White Sox vs San Diego Padres record all-time?

Across 15 all-time meetings, the San Diego Padres lead the series 10-5.

What is the ATS trend in Chicago White Sox vs San Diego Padres games?

ATS: Chicago White Sox are 10-5 vs the spread in these matchups. San Diego Padres are 5-10.

Do Chicago White Sox vs San Diego Padres games go over or under?

Over/under: games between Chicago White Sox and San Diego Padres have gone over 2 times and under 11 times, with an average combined score of 6.1.

When did Chicago White Sox and San Diego Padres last play?

See Last Meetings section for detailed score, spread, and total data from the most recent Chicago White Sox vs San Diego Padres games.

Where can I see the 5-year Chicago White Sox vs San Diego Padres history?

A 5-year head-to-head page tracks every Chicago White Sox vs San Diego Padres meeting from the last five full seasons. Link at the bottom of this page.

Data coverage: Trendline's head-to-head records include closing-line-graded games from 20222026. Older meetings aren't in this dataset yet.

Head-to-head data derived from closing-line game records. Stats update nightly from graded game results.

For informational and entertainment purposes only. Not betting advice. Please gamble responsibly.

Optimus

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